Sanguine Maria Build Guide Raid Shadow Legends

24 Oct

Written By Ioan

Sanguine Maria Build Guide: best Masteries, Artifacts, Accessories and Blessings

Sanguine Maria is the Fusion Champion for Halloween 2025 in Raid. Sanguine Maria’s entire kit revolves around a new mechanic the divisible by three.

A3 (Gorescream): Removes buffs, hits harder against enemies with buffs divisible by three, and grants an extra turn if she has buffs divisible by three.
A2: Ignores 33% DEF normally, but on every third turn, ignores 99% DEF, Stoneskin, and Block Damage.
A1: Can trigger extra turns for combo rotations. (Does not work against Bosses)

Her passive boosts her damage with each hit (up to +99%) and reduces damage she takes the longer a fight goes on. If enemies revive, she revives too, placing True Fear on them.

Overall, she’s a creative, high-skill champion that rewards precise timing in PvP battles.

Sanguine Maria Game Modes Ratings

    General
    Dungeons
    Potion Farm
    Doom Tower
  
    ★★★★✰ Campaign
    ★★★★✰ Minotaur
    ★★★★✰ Arcane Keep
    ★★★★★ Floors
  
    ★★★★★ Arena Offense
    ★★★✰✰ Spider
    ★★★★✰ Void Keep
    ★★★★✰ Magma Dragon
  
    ★★★★✰ Arena Defense
    ★★★★✰ Fire Knight
    ★★★★✰ Spirit Keep
    ★★★✰✰ Nether Spider
  
    ★★★★✰ Clan Boss
    ★★★★★ Dragon
    ★★★★✰ Force Keep
    ★★★✰✰ Frost Spider
  
    ★★★★✰ Hydra
    ★★★★✰ Ice Golem
    ★★★★✰ Magic Keep
    ★★★✰✰ Scarab King
  
    ★★★★✰ Chimera
    ★★★✰✰ Iron Twins
    
    ★★✰✰✰ Celestial Griffin
  
    ★★★★✰ Amius
    ★★★✰✰ Sand Devil
    
    ★★★★★ Eternal Dragon
  
    ★★★★★ Faction Wars
    ★★★★✰ Phantom Shogun
    
    ★★✰✰✰ Dreadhorn
  
    ★★★★✰ Dark Fae

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Sanguine Maria Builds

Recommended Artifact Sets for Sanguine Maria:

PvE (Player vs. Enemy):
- Items: Merciless, Savage or Lethal, Cruel, Perception, Feral.
- Relics: Wand of Submission, Gorecrescent, Malefic Talon, Dreadbomb.
PvP (Player vs. Player):
- Items: Merciless, Savage or Lethal, Cruel, Perception, Feral.
- Relics: Wand of Submission, Gorecrescent, Malefic Talon, Dreadbomb.

Recommended Stats for Sanguine Maria:

  
    Artifacts: Main Stat
    Accessories: Main Stat
  
    Weapon: ATK
    Gauntlets: C.DMG%, C.RATE%, ATK%
    Ring: ATK
  
    Helmet: HP
    Chestplate: ATK%
    Amulet: C.DMG%
  
    Shield; DEF
    Boots: SPD, ATK%
    Banner: ATK, ACC
  
    Stats Priority
  
    PvE: ATK%, C.RATE, C.DMG, SPD, ACC
  
    PvP: ATK%, C.RATE, C.DMG, SPD, ACC

How to get Sanguine Maria:

Ancient Shard
Sacred Shard
Primal Shard
Halloween Fusion 2025

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Best Sanguine Maria Blessings

One of the best Blessings for Sanguine Maria is Phantom Touch, this will help you in any content in RAID. However, if you’re aiming to build Sanguine Maria for other specific Game Modes, check out the table below for tailored recommendations.

    Blessings Recommendation
    Game Mode
  
    Phantom Touch (DMG)
    1-4* Awakening
  
    Crushing Rend (Bosses)
    5-6* Awakening
  
    Lightning Cage (Waves/Arena)
    1-6* Awakening

Sanguine Maria Masteries

Here are some of the best Masteries to choose for Sanguine Maria in Both PvE and PvP activities:

1. Best overall Masteries for Sanguine Maria in PvE, PvP and Bossing:

Offense — Deadly Precision, Keen Strike, Shield Breaker, Ruthless Ambush, Opportunist, Single Out, Bring it Down, Methodical, Kill Streak, Warmaster.
Defense — Tough Skin, Blastproof, Resurgent, Delay Death, Retribution.